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Products > Antituberculosis Agent > Isoniazid

Isoniazid

Synonyms: Nydrazid

Isoniazid is an antibiotic that is used to kill the bacteria that cause tuberculosis (TB). Its exact mechanism of action is unknown but it is thought to prevent the bacteria from making components called mycolic acids which are needed to form cell walls. It combines with an enzyme which interferes with the cell metabolism of the bacteria. As a result of the disruption of its metabolism and without a cell wall the bacteria die.

Package	Price	Per Pill	Savings
Isoniazid 300mg
30 pills x 300mg	$3.3	$0.11 per pill
60 pills x 300mg	$6.44	$0.11 per pill	$0.16
90 pills x 300mg	$9.41	$0.1 per pill	$0.49
120 pills x 300mg	$12.21	$0.1 per pill	$0.99

Package	Price	Per Pill	Savings
Isoniazid 400mg
30 pills x 400mg	$4.8	$0.16 per pill
60 pills x 400mg	$9.36	$0.16 per pill	$0.24
90 pills x 400mg	$13.68	$0.15 per pill	$0.72
120 pills x 400mg	$17.76	$0.15 per pill	$1.44

Indication:

Tuberculosis caused by human, bovine, and BCG strains of Mycobacterium tuberculosis. Not to be used as the sole tuberculostatic agent. Prophylaxis of tuberculosis. Investigational: To improve severe tremor in clients with multiple sclerosis

How to take:

Active tuberculosis, Adults: 5 mg/kg/day (up to 300 mg/day) as a single dose;
Prophylaxis, Adults: 300 mg/day in a single dose; Please see label. For more detailed information please consult specialist. Do not take more of Isoniazid 300mg than it is indicated at the label without consulting your doctor.

Precautions:

Do not violate instructions. Severe and sometimes fatal hepatitis may occur even after several months of therapy; incidence is age-related and current alcohol use increases the risk. Increased risk of fatal hepatitis in minority women, especially Blacks and Hispanics; also increased risk postpartum. Extreme caution should be exercised in clients with convulsive disorders, in whom the drug should be administered only when the client is adequately controlled by anticonvulsant medication. Also, use with caution for the treatment of renal tuberculosis and, in the lowest dose possible, in clients with impaired renal function and in alcoholics.